Microplates 384 Well Small Volume™ HiBase & LoBase Greiner Bio-One

   

A small sample volume is an important goal in high-throughput screening. The substances to be tested and the reagents used are usually scarce, expensive and time-consuming to produce. In addition to a high degree of automation and the use of sensitive reader systems, the introduction of higher format microplates, such as the 384 well or the 1536 well microplate, has made a decisive contribution to reducing the sample volume.

The potential for savings in the 384 well microplate with an average working volume of 70 – 80 μl is relatively limited and successful use of 1536 well microplates requires considerable optimisation work on the instrumentation to be used. In order to enable a savings potential in the 384 well format comparable to a 1536 well microplate, Greiner Bio-One developed a new platform with the 384 well Small Volume™ microplates. They have round wells with a conical geometry (Fig. 1). The wells have a total volume of 28 μl and a working volume of between 4 μl and 25 μl.

384 well Small VolumeTM HiBase polystyrene microplates:

• Perfect for top reading even at low working volumes
• Savings in reagent similar to 1536 well microplates
• Suited for transmission, fluorescence and luminescence applications
• Excellent optical properties